Myeloma mortality statistics

Deaths

Deaths from myeloma, 2017-2019, UK.

Proportion of all deaths

Percentage myeloma is of total cancer deaths, 2017-2019, UK.

 

Age

Peak rate of myeloma deaths, 2017-2019, UK

 

Trend over time

Change in myeloma mortality rates since the early 1970s, UK

Myeloma is the 17th most common cause of cancer death in the UK, accounting for 2% of all cancer deaths (2017-2019).[1-4]

In females in the UK, myeloma is the 16th most common cause of cancer death (2% of all female cancer deaths). In males in the UK, it is the 16th most common cause of cancer death (2% of all male cancer deaths).

44% of myeloma deaths in the UK are in females, and 56% are in males (2017-2019).

Myeloma mortality rates (European age-standardised Open a glossary item (AS) rates) in the UK are significantly lower in females than in males (2017-2019).

Myeloma mortality rates (European age-standardised Open a glossary item (AS) rates) for persons are similar to the UK average in all the UK constituent countries.

For myeloma, mortality rates do not vary between UK constituent nations however incidence rates do vary between the UK constituent nations.

Myeloma (C90), Annual Average Number of Deaths, Crude and European Age-Standardised (AS) Mortality Rates per 100,000 Persons Population, UK, 2017-2019

  England Scotland Wales Northern Ireland UK
Female Deaths 1,148 111 67 36 1,361
Crude Rate 4.1 4.0 4.2 3.7 4.0
AS Rate 3.9 3.7 3.6 4.0 3.9
AS Rate - 95% LCL 3.8 3.3 3.1 3.2 3.8
AS Rate - 95% UCL 4.0 4.1 4.1 4.8 4.0
Male Deaths 1,461 144 82 48 1,736
Crude Rate 5.3 5.4 5.3 5.2 5.3
AS Rate 6.3 6.5 5.5 6.9 6.3
AS Rate - 95% LCL 6.1 5.9 4.8 5.8 6.1
AS Rate - 95% UCL 6.4 7.1 6.2 8.0 6.4
Persons Deaths 2,610 255 149 84 3,098
Crude Rate 4.7 4.7 4.7 4.5 4.7
AS Rate 4.9 4.9 4.5 5.3 4.9
AS Rate - 95% LCL 4.8 4.5 4.1 4.6 4.8
AS Rate - 95% UCL 5.0 5.2 4.9 5.9 5.0

95% LCL and 95% UCL are the 95% lower and upper confidence limits around the AS Rate Open a glossary item

References

  1. England and Wales data were accessed from Nomis mortality statistics by underlying cause, sex and age, November 2021: Nomis mortality statistics by underlying cause, sex and age.
  2. Scotland data were provided by ISD Scotland on request, November 2021. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications/index.asp(link is external).
  3. Northern Ireland data were provided by the Northern Ireland Cancer Registry on request, February 2022. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/.
  4. Population data were published by the Office for National statistics, accessed July 2020. The data can be found here: Population estimates for the UK, England and Wales, Scotland and Northern Ireland, provisional: mid-2019.

About this data

Data is for UK, 2017-2019, C90.

Last reviewed:

Myeloma mortality is strongly related to age, with the highest mortality rates being in older people. In the UK in 2017-2019, on average each year around 6 in 10 deaths (61%) were in people aged 75 and over.[1-4] This largely reflects higher incidence and lower survival for myeloma in older people.

Age-specific mortality rates rise steadily from around age 45-49 and more steeply from around age 65-69. The highest rates are in the 85 to 89 age group for females and the 90+ age group for males. Mortality rates are significantly lower in females than males in a number of (mainly older) age groups. The gap is widest at age 50 to 54, when the age-specific mortality rate is 2 times lower in females than males.

Myeloma (C90), Average Number of Deaths per Year and Age-Specific Mortality Rates per 100,000 Persons Population, UK, 2017-2019

References

  1. England and Wales data were accessed from Nomis mortality statistics by underlying cause, sex and age, November 2021: Nomis mortality statistics by underlying cause, sex and age.
  2. Scotland data were provided by ISD Scotland on request, November 2021. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications/index.asp(link is external).
  3. Northern Ireland data were provided by the Northern Ireland Cancer Registry on request, February 2022. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/.
  4. Population data were published by the Office for National statistics, accessed July 2020. The data can be found here: Population estimates for the UK, England and Wales, Scotland and Northern Ireland, provisional: mid-2019.

About this data

Data is for UK, 2017-2019, ICD-10 C90.

Last reviewed:

Myeloma age-standardised (AS) Open a glossary item rates for females and males combined increased by 57% in the UK between 1971-1973 and 2017-2019.[1-4] The increase was larger in males than in females.

For females, myeloma AS mortality rates in the UK increased by 41% between 1971-1973 and 2017-2019. For males, myeloma AS mortality rates in the UK increased by 68% between 1971-1973 and 2017-2019.

Over the last decade in the UK (between 2007-2009 and 2017-2019), myeloma AS mortality rates for females and males combined remained stable. In females AS mortality rates remained stable, and in males rates remained stable.

Myeloma (C90), European Age-Standardised Mortality Rates per 100,000 Persons Population, UK, 1971-2019

For most cancer types, mortality trends largely reflect incidence and survival trends. For example, rising mortality may reflect rising incidence and stable survival, while falling mortality may reflect rising incidence and rising survival.

Myeloma mortality rates have varied between age groups in females and males combined in the UK since the early 1970s.[1-4] Rates in 0-24s have remained stable, in 25-49s have decreased by 46%, in 50-59s have decreased by 27%, in 60-69s have decreased by 13%, in 70-79s have increased by 61% and in 80+s have increased by 225%.

Myeloma (C90), European Age-Standardised Mortality Rates per 100,000 Persons Population, By Age, UK, 1971-2019

References

  1. England and Wales data were accessed from Nomis mortality statistics by underlying cause, sex and age, November 2021: Nomis mortality statistics by underlying cause, sex and age.
  2. Scotland data were provided by ISD Scotland on request, November 2021. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications/index.asp(link is external).
  3. Northern Ireland data were provided by the Northern Ireland Cancer Registry on request, February 2022. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/.
  4. Population data were published by the Office for National statistics, accessed July 2020. The data can be found here: Population estimates for the UK, England and Wales, Scotland and Northern Ireland, provisional: mid-2019.

About this data

Data is for UK, 1971-2019, C90.

Cancers in children and young people (aged 0-24) are best classified using a different system to cancers in adults, so the figures presented here may not correspond with those elsewhere.

Last reviewed:

It is projected that the average number of deaths from myeloma in the UK every year will rise from around 3,600 deaths in 2023-2025 to around 4,500 deaths in 2038-2040.[1]

Myeloma mortality rates are projected to fall by 3% in the UK between 2023-2025 and 2038-2040, to 5 deaths per 100,000 people on average each year by 2038-2040.[1] This includes an increase in rates for males and a decrease for females.

For females, myeloma European age-standardised (AS) Open a glossary item mortality rates in the UK are projected to fall by 9% between 2023-2025 and 2038-2040, to 4 deaths per 100,000 per year by 2038-2040.[1] For males, AS rates are projected to rise by less than 1% between 2023-2025 and 2038-2040, to 7 deaths per 100,000 per year by 2038-2040.[1]

Myeloma (C90), Observed and Projected Age-Standardised Mortality Rates, by Sex, UK, 1975-2040

Download the data table (xlsx)

References

Calculated by the Cancer Intelligence Team at Cancer Research UK, February 2023. Age-period-cohort modelling approach described here, using 2020-based population projections (Office for National Statistics) and observed cancer mortality data (1975-2018).

About this data

Projections are based on mortality data from 1975-2018 (England, Scotland, Wales and Northern Ireland); the above figure presents all UK data from 1975-2018 (observed) and 2019-2040 (projected). Number of deaths and age-standardised rates are presented as annual averages for each 3-year rolling period. ICD-10 codes C90.

Projections are based on observed mortality rates and therefore implicitly include changes in cancer risk factors, diagnosis and treatment. Confidence intervals are not calculated for the projected figures. Projections are by their nature uncertain because unexpected events in future could change the trend. It is not sensible to calculate a boundary of uncertainty around these already uncertain point estimates. Changes are described as 'increase' or 'decrease' if there is any difference between the point estimates.

More on projections methodology

Last reviewed:

There is no evidence for an association between myeloma mortality and deprivation for either males or females in England.[1] England-wide data for 2007-2011 show European age-standardised Open a glossary item mortality rates are similar for both males and females living in the most deprived areas compared with the least deprived.[1]

Myeloma (C90), European Age-Standardised Mortality Rates by Deprivation Quintile, England, 2007-2011

The estimated deprivation gradient in myeloma mortality between people living in the most and least deprived areas in England has not changed in the period 2002-2011.[1]

References

  1. Cancer Research UK and National Cancer Intelligence Network. Cancer by deprivation in England: Incidence, 1996-2010, Mortality, 1997-2011. London: NCIN; 2014.

About this data

Data is for: UK, 2007-2011, ICD-10 C90

Deprivation gradient statistics were calculated using mortality data for 2007-2011. The deprivation quintiles were calculated using the Income domain scores from the Index of Multiple Deprivation (IMD) from the following years: 2004, 2007 and 2010. Full details on the data and methodology can be found in the Cancer by Deprivation in England NCIN report.

Last reviewed:

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