All cancer types, Secondary cancers
Open
Phase 2
This trial is looking at matching targeted treatment to people who have a rare cancer. It is also looking at matching targeted treatment to people with a common cancer that has a rare gene change (mutation) in the cancer cells.
This trial is for people whose cancer has come back or got worse despite treatment. It is also for people when there is no standard treatment available for them.
The trial is for adults, teenagers and children. We use the term ‘you’, but of course if you are a parent, we are referring to your child.
Cancer Research UK supports this trial.
Recruitment start: 16 November 2022
Recruitment end: 30 November 2029
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Dr Matthew Krebs
Cancer Research UK (Centre for Drug Development)
University of Manchester
The Royal Marsden NHS Foundation Trust
University of Birmingham
Roche
You can find out more about this trial on the DETERMINE website.
This is Cancer Research UK trial number CRUKD/21/004.
Last reviewed: 11 March 2025
CRUK internal database number: 17663