Types of neuroendocrine cancer

Neuroendocrine cancers are a group of cancers that start in the neuroendocrine system Open a glossary item. You might also hear the term neuroendocrine neoplasm (NEN). This means the same as neuroendocrine cancer.

There are 2 key groups of neuroendocrine cancer: 

  • neuroendocrine tumours (NETs Open a glossary item)
  • neuroendocrine carcinomas (NECs Open a glossary item)

Neuroendocrine cancer can start in any part of the body. Doctors often name them after the part of the body where they develop. They call this the primary Open a glossary item site. They also name some NETs after the type of hormone they make.

To find out more about the your type of neuroendocrine cancer, you can look it up on our list below.

Neuroendocrine carcinoma (NEC)

Neuroendocrine Carcinomas (NECs) are different to neuroendocrine tumours (NETs). The cancer cells look very abnormal and grow rapidly. Treatment is different.

Lung neuroendocrine cancer

There are different groups of lung neuroendocrine cancer. Lung neuroendocrine tumours (NETs) include typical and atypical carcinoids. Lung neuroendocrine carcinomas (NECs) include small cell and large cell NECs.

Stomach neuroendocrine cancer

Stomach neuroendocrine cancers start in the neuroendocrine cells of the stomach. Neuroendocrine cells in the stomach help control the release of digestive juices and how fast food moves through the stomach.

Small bowel neuroendocrine cancer

Small bowel neuroendocrine cancers start in the neuroendocrine cells of the small bowel (small intestine). Cancers can develop in the different parts of the small bowel including the ileum, jejunum and duodenum.

Large bowel and rectal neuroendocrine cancer

Large bowel and rectal neuroendocrine cancers are less common than other types of bowel cancer. They develop in the neuroendocrine cells of the large bowel (colon) or back passage (rectum).  

Pancreatic neuroendocrine cancers

There are different types of neuroendocrine cancer that develop in the pancreas. Pancreatic neuroendocrine tumours (NETs) include insulinoma, gastrinoma, somatostatinoma, glucagonoma and VIPoma.

Non functioning pancreatic neuroendocrine tumours (NETs)

Non functioning pancreatic NETs are the most common type of pancreatic NET. Non functioning means they don’t over produce hormones, or cause a set of symptoms (syndrome).

Insulinoma

Insulinomas are rare neuroendocrine tumours (NETs) that start in the pancreas. They make the hormone insulin which controls the amount of sugar (glucose) in your body.

Gastrinoma

Gastrinomas are rare neuroendocrine tumours (NETs) that develop in the pancreas or duodenum. They make large amounts of the hormone gastrin.

Glucagonoma

Glucagonomas are very rare NETs that develop in the pancreas. Glucagonomas usually make large amounts of glucagon which raises your blood sugar levels.

VIPoma

VIPomas are rare pancreatic NETs that start in the cells that make the hormone VIP. VIP relaxes the stomach and bowel muscles and affects sugar, salt and water levels in your gut.

Somatostatinoma

Somatostatinomas are rare neuroendocrine tumours (NETs). They develop in the pancreas and the duodenum. Most somatostatinomas make large amounts of the hormone somatostatin.

Last reviewed: 
05 Feb 2025
Next review due: 
05 Feb 2028
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