Treatment
Metastatic prostate cancer means your cancer began in the prostate and has spread to another part of your body such as the bones. It is also known as advanced prostate cancer.
Find out more about metastatic prostate cancer
Symptoms of metastatic prostate cancer depend on where the cancer has spread to. Symptoms might include:
tiredness and feeling unwell
bone pain
breathlessness
problems passing urine
weight loss and loss of appetite
bowel problems
sexual problems such as difficulty getting an erection
swelling
The symptoms can be difficult to cope with. But your doctors and nurses can support you and give you treatments to help relieve the symptoms.
Treatments such as chemotherapy, radiotherapy or hormone therapy might shrink the cancer, reduce symptoms and help you feel better. You can also have other medicines to help relieve symptoms, such as painkillers.
Find out about treatments for metastatic prostate cancer
There are symptom control teams in most cancer units. They can help you to stay as well as possible for as long as possible. They are also in hospices and many general hospitals.
Most symptom control teams have home care services to visit you at home.
Find out who can support you at home
Tiredness (fatigue) is a common symptom of advanced cancer. You may feel that you lack energy, and this can be overwhelming.
Let your doctor or nurse know if you’re very tired, as they can prescribe medicines or other treatments to help. For example, a blood transfusion can give you more energy if you’re tired due to .
It’s important to rest a few times throughout the day. Resting regularly can help you feel less tired and more able to cope. You don't have to sleep during these times. Just sitting or lying down will help.
Exercising can be hard when you feel very tired. But research shows that daily light to moderate exercise can give you more energy. You can try a short walk if you can manage it. Gentle exercises in bed or standing up can help if you can’t move around easily.
Your hospital physiotherapist might be able to help you plan an exercise programme that suits your needs.
You might feel more tired if you have trouble sleeping at night. Some medicines like can also cause difficulty sleeping. It can help to change a few things about when and where you sleep.
Find out how cancer fatigue can be managed and treated
It is common to have pain if your cancer has spread to your bones. Your bones might be weaker, so they could break more easily. Treating the cancer helps to control bone damage and pain.
Having pain has a big impact on how your feel in yourself and interferes with your daily life. It is important to talk to your healthcare team if you have pain so they can help you manage it.
The prostate cancer treatment might help with your pain. But there are other ways of managing pain. Your specialist might suggest:
and a type of called radium 223
painkillers
surgery
There are different painkillers (analgesics) that might help. If one doesn't work, tell the team looking after you so they can prescribe something else.
Find out more about pain control
Bisphosphonate drugs can help to reduce bone damage. They slow down the damage caused by cancer cells. There are different types of bisphosphonates. You might have it as a drip into the vein (intravenously). Or take a tablet by mouth.
You might also take calcium and vitamin D supplements. Your doctor will tell you about this.
Find out more about treating bone problems
Cancer that has spread into the spinal bones can cause pressure on the spinal cord. This is called spinal cord compression. The pressure on the spinal cord stops the nerves from working normally. This can cause:
back pain
changes in sensation, such as tingling or numbness
changes in the way your bowel or bladder work
difficulty walking
Find out more about treating spinal cord compression
You might feel breathless if the cancer has spread to your lungs or if you have anaemia. You can learn breathing techniques that can help. You might need a to give you red blood cells if you have anaemia.
Tell your doctor or nurse if you feel breathless. They can prescribe medicines to make your breathing easier.
Find out about treating breathlessness
You might have problems passing wee (urine) if your cancer presses on the . Also, if your cancer spreads to your urethra and bladder this can make it difficult to pass urine.
You might:
pass urine more often
need to get up in the night to pass urine
have difficulty passing urine
suddenly not be able to pass urine (acute urine retention)
have a strong urge to empty your bladder
have blood in your urine or semen
have kidney problems
leak urine (incontinence)
Treatments depend on the cause of the problem. You might:
have a tube into your bladder (catheter) to drain the urine
take drugs called alpha blockers to help relax the muscles around the opening of the bladder
have surgery to stop the blockage - this is called trans urethral resection of the prostate (TURP)
do pelvic floor muscle exercises to strengthen the muscles that help you pass urine
use pads or pants to absorb any urine leakage
If cancer blocks the , you might have a tube put into your kidney. This is to drain wee outside of your body. Or you might have a put into the ureter to keep it open. Sometimes you might have radiotherapy to make the cancer smaller to relieve the blockage.
Find out more about having a trans urethral resection of the prostate (TUR or TURP)
You might not feel like eating and may lose weight. It is important to eat as much as you can.
Tips
Eating several small meals and snacks throughout the day can be easier to manage.
Ask your doctor to recommend high calorie drinks to sip between treatments if you are worried about losing weight.
Eat whatever you feel like eating rather than what you think you should eat.
Make up calories between treatments for the days when you really don’t feel like eating.
Drink plenty of fluids even if you can't eat.
Don't fill your stomach with a large amount of liquid before eating.
Try to eat high calorie foods to keep your weight up.
Feeling sick can also stop you from eating. Speak to your doctor or nurse about taking anti sickness medicines if you feel sick.
Read more about diet problems and cancer
These include frequent or loose poo or a feeling that you have to rush to the toilet (urgency). If you’ve had radiotherapy you might feel the need to strain whether or not you need to poo.
You might have constipation if you’re taking certain painkillers or if you’re less active than usual. Speak to your doctor or nurse if you feel constipated.
Find out more about bowel problems with cancer
Advanced prostate cancer can affect how you feel about yourself, your sex life and your relationships. You might have problems such as:
difficulty getting an erection
having less interest in sex
changes in how your body looks and feels
If you have a partner it can be hard to cope if you can’t have sex. This can affect your self image and you might feel sad or depressed. Speak to your partner about your concerns. Keep in mind that you can still be intimate with them through cuddling and kissing.
Speak to your doctor or nurse about any sexual problems. They are used to discussing these issues and can offer support or refer you to a sex therapist.
Find out about sex and relationships
You might have swelling called lymphoedema if the cancer has spread to the lymph glands in the groin or pelvis. The swelling might be in:
one or both legs
the lower part of the tummy (abdomen)
the genital area
Make sure you don’t get skin infections because these increase the risk of swelling.
Lymphoedema can be difficult to cope with. Lymphoedema practitioners can offer treatment and support. Speak to your doctor or nurse if you notice any swelling.
Find out more about lymphoedema
You might find it difficult to cope when you are diagnosed with metastatic or advanced cancer.
It is common for people with metastatic prostate cancer to feel sad or become depressed. The hormone treatment can also affect your mood. You may find it helpful to understand this as a part of your illness. Talk to your specialist nurse about how you are feeling. They can arrange for more support if you need it.
Last reviewed: 23 Jul 2025
Next review due: 23 Jul 2028
Metastatic prostate cancer has spread to other parts of your body. Treatment options include chemotherapy and hormone therapy.
Prostate cancer can spread to other parts of the body. When this happens, it is called metastatic or advanced prostate cancer.
The symptoms of metastatic or advanced prostate cancer depend on where the cancer has spread to. They might include bone pain and tiredness.
Get practical and emotional support to help you cope with a diagnosis of prostate cancer, and life during and after treatment.
Research is looking into diagnosing and treating prostate cancer. You need to talk to your specialist if there are any trials that you think you might be able to take part in.
Prostate cancer is cancer that starts in the prostate gland. The prostate gland is found at the base of the bladder and is about the size of a walnut.

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