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A trial looking at chemotherapy before surgery for bowel cancer (FOxTROT)

Overview

Cancer types:

Bowel (colorectal) cancer, Colon cancer

Status:

Results

Phase:

Phase 3

Details

This trial looked at whether treatment before as well as after surgery can help stop bowel cancer coming back.

The trial was supported by Cancer Research UK. It was open for people to join between 2008 and 2016. The research team presented some results at a conference in 2019, and published more results in 2023 and 2025.

Recruitment start: 15 May 2008

Recruitment end: 23 December 2016

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Professor Dion Morton

Supported by

Bobby Moore Fund (BMF)

Cancer Research UK

Experimental Cancer Medicine Centre (ECMC)

NIHR Clinical Research Network: Cancer

Other information

This is Cancer Research UK trial number CRUK/07/014.

There is more information about this and the other FOxTROT trials on the FOxTROT website(link is external).

Last reviewed: 28 May 2025

CRUK internal database number: 895

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