What is chronic myeloid leukaemia (CML)?

Chronic myeloid leukaemia (CML) is a type of cancer that affects the blood and bone marrow. It usually develops very slowly. 

Symptoms of chronic myeloid leukaemia (CML)

Many people with chronic myeloid leukaemia (CML) won't have any symptoms at all. Some of the common symptoms can include feeling full or tummy discomfort, swollen lymph nodes Open a glossary item, feeling weak and weight loss.

Getting diagnosed with chronic myeloid leukaemia (CML)

You usually start by seeing your GP if you have symptoms that could be due to CML. Or your GP might arrange to see you if you have had an abnormal blood test result. They will then decide whether to refer you for further tests or to see a specialist. 

Survival for chronic myeloid leukaemia (CML)

Survival for chronic myeloid leukaemia (CML) depends on several factors including age. These figures can only give you a general guide about survival for CML.

Treatment for chronic myeloid leukaemia (CML)

Targeted cancer drugs called tyrosine kinase inhibitors (TKIs) are the main treatment for CML. Find out more about your treatment options, the different treatments and how they monitor treatment is working. 

Stages (phases) of chronic myeloid leukaemia (CML)

There are 2 systems to describe how far your CML has developed. You might have 2 or 3 phases. At the moment CML is mainly described using 3 phases. These are chronic, accelerated and blast. Knowing the phase helps your doctor decide which treatment you need.

Research and clinical trials for chronic myeloid leukaemia (CML)

Research is looking into improving treatment for CML. Find out about the latest UK research and how you can take part in trials.

Living with chronic myeloid leukaemia (CML)

Chronic myeloid leukaemia (CML) is often a slowly developing condition. Treatment can keep it under control for many years. Find out how to cope and what support is available.
 

Risks and causes of chronic myeloid leukaemia (CML)

We don’t know what causes most cases of chronic myeloid leukaemia (CML). But we know that exposure to radiation can increase your risk of developing CML. 

Last reviewed: 
29 May 2025
Next review due: 
29 May 2028